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Degradation of phenanthrene and anthracene by cell suspensions of Mycobacterium sp. strain PYR-1

Article Abstract:

Researchers describe a novel metabolic pathway in Mycobacterium sp. strain PYR-1 for degrading phenanthrene and anthracene. This might be due to different dioxygenases or to a greater substrate variability on the part of the same dioxygenase.

Author: Freeman, James P., Cerniglia, Carl E., Moody, Joanna D., Doerge, Daniel R.
Publisher: American Society for Microbiology
Publication Name: Applied and Environmental Microbiology
Subject: Biological sciences
ISSN: 0099-2240
Year: 2001
Mycobacterium

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Regio- and stereoselective metabolism of 7,12-dimethylbenz[a]anthracene by Mycobacterium vanbaalenii PYR-1

Article Abstract:

Research examines the biodegradation of the carcinogenic polycyclic aromatic hydrocarbon 7,12-dimethylbenz[a]anthracene by Mycobacterium vanbaalenii PYR-1. The biodegradation process involves dioxygenation and monooxygenation reactions and proceeds in a highly regio- and stereoselective manner.

Author: Freeman, James P., Cerniglia, Carl E., Moody, Joanna D., Fu, Peter P.
Publisher: American Society for Microbiology
Publication Name: Applied and Environmental Microbiology
Subject: Biological sciences
ISSN: 0099-2240
Year: 2003
United States, Cyclic crudes and intermediates, Cyclic Crude and Intermediate Manufacturing, Anthracine, Analysis, Physiological aspects, Cocarcinogens, Carcinogens, Polycyclic aromatic compounds, Anthracene

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Initial oxidation products in the metabolism of pyrene, anthracene, fluorene, and dibenzothiophene by the white rot fungus Pleurotus ostreatus

Article Abstract:

The white rot fungus Pleurotus ostreatus metabolizes pyrene and anthracene to form trans dihydrodiols. Pyrene trans-4,5-dihydrodiol is mainly the R,R enantiomeric form while anthracene trans 1,2-dihydrodiol is mainly the S,S form. Fluorene is metabolized to 9-fluorenol and 9-fluorenone, and dibenzothiophene to its sulfoxide and sulfone. The metabolism products suggest the involvement of a cytochrome P-450 monooxygenase in the reaction. The results of the study indicate that the metabolism of polycyclic aromatic hydrocarbons by P. ostreatus is similar to that by nonligninolytic fungi.

Author: Freeman, James P., Cerniglia, Carl E., Fu, Peter P., Hadar, Yitzhak, Bezalel, Lea
Publisher: American Society for Microbiology
Publication Name: Applied and Environmental Microbiology
Subject: Biological sciences
ISSN: 0099-2240
Year: 1996
Polycyclic aromatic hydrocarbons, Pleurotus ostreatus

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Subjects list: Research, Microbial metabolism, Biodegradation
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