Interactions between oral bacteria: Inhibition of Streptococcus mutans bacteriocin production by Streptococcus gordonii

Article Abstract:

An attempt is made to demonstrate that Streptococcus mutans bacteriocin production is a quorumsensing-controlled phenomenon and the role of interactions with other oral bacteria on bacteriocin production by S. mutans is established. A gene, named for Streptococcus gordonii challisin was identified using transpson Tn916 mutagenesis, which is responsible for the inhibition of S. mutans bacteriocin production by S. gordonii Challis.

Physiological aspects, Mutagenesis, Bacteriocins

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Role of the C-terminal direct repeating units of the Streptococcus mutans glucosyltransferase-S in glucan binding

Article Abstract:

The C-terminal of the glucan-binding domain (GBD) with five repeating units of 65 amino acids each, is necessary for the glucosyltransferase (GFT) enzymes of Streptococcus mutans to bind glucan. An antibody-independent binding assay shows that if the C-terminal is removed, GFT is unable to bind glucan but if the N-terminal catalytic domain is removed glucan-binding is unaffected.

Glucans

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LuxS-based signaling affects Streptococcus mutans biofilm formation

Article Abstract:

The role of autoinducer-2 (AI-2) on Streptococcus mutans biofilm formation is examined by constructing a GS-5 luxS-null mutant. The results suggest that the regulation of the glucosyltransferase genes required for sucrose-dependent biofilm is regulated by AI-2.

United States, Microbial mats, Transferases

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