MHC-I recognition by receptors on myelomonocytic cells: New tricks for old dogs?

Article Abstract:

The immunoregulatory properties of MHC-I receptors on myelomonocytic are described and it is proposed that they respond to changing levels and forms of MHC-I. Since myelomonocytic MHC-I receptors recognise a wide range of alleles and MHC-I structures, it is proposed that their task is to distinguish between expression levels and folding forms of MHC.

Ir genes

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The complete genome sequence of a dog: A perspective

Article Abstract:

A complete, high-quality reference sequence of a dog genome was produced by a team of researches, achieving another milestone in deciphering the genomic landscape of mammalian organisms. The genome sequence provides an indispensable resource for comparative analysis and novel insights into dog and human evolution and history.

United States, Nucleotide sequence, Base sequence, Animal genetics

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Is it genomic imprinting or preferential expression?

Article Abstract:

The study helps in explaining the phenomenon of imprinted genes in humans, which are actually found to be monoallellically expressed in a parent-of-origin-specific manner. The results show that most of the imprinted genes show differential allelic expression.

Gene expression, Genomic imprinting

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