Modulated expression of type X collagen in the Meckel's cartilage with different developmental fates

Article Abstract:

Type X collagen does not appear to be associated with hypertrophic cartilage matrix formation in the distal part of Meckel's cartilage. However, a role in endochondral ossification is indicated by the spatial distribution of type X collagen only in the caudal region of Meckel's cartilage. The study also suggests that the molecular mechanism of type X collagen expression is related to differential development in Meckel's cartilage. Type X collagen's presence or absence may be a key to understanding the regulation of phenotypic transformation in Meckel's cartilage and the molecular basis of mandible evolution from non-mammalian to mammalian species.

Collagen, Cartilage

---

Identification and localization of endothelin-1 and its receptors in human fetal jaws

Article Abstract:

A study was conducted to examine the role of the endothelin-1 (ET-1) gene and its receptors in the development of human fetal craniofacial tissues of nine- to 12-week old fetuses. Radioligand binding studies revealed localization of ET-1 in the epithelial cells of the oral cavity and showed high concentrations of its receptors in the membranes of the fetal jaws. Autoradiography revealed localization of binding sites in the embryonic mandibular process of the oral cavity. This suggests that ET-1 contributes in the formation of the human mandible.

Endothelin

---

Lethality of Rw\Rw mouse embryos during early postimplantation development

Article Abstract:

Genetic and physical mapping studies prove that the rump white (Rw) mutation in the mouse is associated with a large chromosomal inversion, based on segregation analysis of the mutant phenotype in heterozygous mice. Three mutations on mouse chromosome 5, white spotting (W), patch (Ph), and Rw produce pigmentation disorders. The W phenotype results from a mutation altering the c-kit protooncogene and Ph with the deletion of Pdgfra.

Analysis, Chromosome mapping, Mutation (Biology), Mutation

Similar abstracts:

• Abstracts: Slow and fast muscle fibres are preferentially derived from myoblasts migrating into the chick limb bud at different developmental times
• Abstracts: Ectopic expression of the flagellar regulon alters development of the Bordetella-host interaction. Cystic fibrosis airway epithelia fail to kill bacteria because of abnormal airway surface fluid
• Abstracts: undulated phenotypes suggest a role of Pax-1 for the development of vertebral and extravertebral structures. Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo
• Abstracts: Reproductive characteristics of migratory golden eagles in Denali National Park, Alaska. Genetic variation and nesting Bald Eagles
• Abstracts: Regulation of pectin methylesterase and polygalacturonate lyase activity during differentiation of infection structures in Uromyces viciae-fabae

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.