Analysis of the role of OpuC, an osmolyte transport system, in salt tolerance and virulence potential of Listeria monocytogenes

Article Abstract:

The OpuC betaine transport system of Listeria monocytogenes is essential for colonization of the small intestine and subsequent systemic infection in a murine model of listeriosis. Betaine is the major osmolyte in L. monocytogenes, allowing it to survive at high salt concentrations and low temperatures.

Biological transport, Active, Active biological transport

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Molecular and physiological analysis of the role of osmolyte transporters BetL, Gibu, and OpuC in growth if listeria monocytogenes at low temperatures

Article Abstract:

Listeria monocytogenes is a ubiquitous food-borne pathogen found widely distributed in nature as well as an undesirable contaminant in a variety of fresh and processed foods. This uniquity can be atleast partly explained by the ability of the organism to grow at high osmolarity and reduced temperatures, a consequence of its ability to accumulate omo and cryoprotective compounds termed osmolytes.

Causes of, Risk factors, Microbiology, Food poisoning, Pathogenic microorganisms

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Role for HtrA in stress induction and virulence potential in Listeria monocytogenes

Article Abstract:

Listeria monocytogenes genome in silico analysis revealed lmo0292, a gene predicted to encode a HtrA-like serine protease. It suggested that Listeria monocytogenes lmo292 encodes an HtrA-like serine protease that is not part of the classical heat shock response but is involved in stress responses and virulence.

Genetic aspects, Bacterial genetics, Serine

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