A kinesin-like protein is required for germ plasm aggregation in Xenopus

Article Abstract:

The role of a Xenopus kinesin-like protein, Xklp1, in cytoplasmic localization is investigated. The protein has already been shown to have a role in mitosis. Results show that depletion of Xklp1 mRNA in oocytes hampers germ plasm aggregation in the embryo, so Xklp1 is in fact necessary for aggregation of early Xenopus embryos. It therefore has a prominent and developmentally significant role in cytoplasmic localization.

Microbial aggregation, Kinesin

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Maternal XTcf1 and XTcf4 have distinct roles in regulating Wnt target genes

Article Abstract:

The contribution of transcription factors XTcf1 and XTcf4 in the expression of genes responsible for WNT signaling pathway in Xenopus embryos is studied.

United States, Netherlands, Science & research, Genetic aspects, Cellular signal transduction, Embryology, Experimental, Embryological research, DNA binding proteins

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