New insights into the interaction of Ras with the plasma membrane

Article Abstract:

Studies have revealed that intracellular membranes and vesicular transport are significantly involved in the passage of Ras proteins to the inner surface of the plasma membrane. The farnesylation of the cysteine of the C-terminal CAAX motif is the first component that facilitate Ras protein localization to the plasma membrane. The second component is proteolytic removal of the AAX residues. Such process will lead to the carboxyl methylation of the C terminus.

Cells, Cell membranes, Cell permeability, Plasma membranes, Ras genes

---

Roles for proteolysis and trafficking in notch maturation and signal transduction

Article Abstract:

Experiments performed by various groups confirm the validity of the proteolysis model of Notch signaling as well as the roles of proteolysis and trafficking of Notch during receptor maturation. In these studies, two molecules that undergo similar patterns of proteolysis were examined. These included the beta-amyloid precursor protein and the sterol regulatory element binding protein.

Cellular signal transduction, Cell receptors, Proteolysis

---

Similar abstracts:

• Abstracts: New insights into type II NAD (P) H: Quinone oxidoreductases. Type V Protein secretion pathway: The autotransporter story
• Abstracts: The E. coli signal recognition particle is required for the insertion of a subset of inner membrane proteins. Dissecting RNA-protein interactions: RNA-RNA recognition by Rop
• Abstracts: Morphometry of the digestive tracts of some passerine birds. Passage rates of digesta markers in the gut of the Hoatzin, a folivorous bird with foregut fermentation
• Abstracts: The E. coli signal recognition particle is required for the insertion of a subset of inner membrane proteins. part 2
• Abstracts: Structure of a cholesterol-binding, thiol-activated cytolysin and a model of its membrane form

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.