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Power to detect QTL in a free-living polygynous population

Article Abstract:

The power to detect quantitative trait loci (QTL) is discussed as it relates to a free-living polygynous population and as used to study a complex red deer pedigree. The power to detect linkage in a complex pedigree was contrasted with that of the half-sib design. In many populations it is not possible to carry out a cross with the organism studied to detect QTL in natural populations. QTL detection may be possible in carefully studied natural populations, but detailed life history data and good pedigree information are essential.

Author: Visscher, P.M., Pemberton, J.M., Slate, J.
Publisher: Blackwell Publishers Ltd.
Publication Name: Heredity
Subject: Biological sciences
ISSN: 0018-067X
Year: 1999
United Kingdom, Scotland, Methods, Genetic aspects, Evolution (Biology), Chromosome mapping, Evolution, Red deer

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The threshold model as a general purpose normalizing transformation

Article Abstract:

The threshold model can be used as a general-purpose normalizing transformation. To show the usefulness of the approach, results from a simulation study that considers the threshold model a transformation for the estimate of both the heritability and the genetic correlation are presented.

Author: Roff, Derek A.
Publisher: Blackwell Publishers Ltd.
Publication Name: Heredity
Subject: Biological sciences
ISSN: 0018-067X
Year: 2001
Canada, Reports

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Subjects list: Statistical Data Included, Research, Usage, Mathematical models, Heredity, Genetic research
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