Protamine-induced permeabilization of cell envelopes of gram-positive and gram-negative bacteria

Article Abstract:

The mechanisms that mediate the antibacterial action of protamine were analyzed in cell suspensions of Listeria monocytogenes, Escherichia coli and Shewanella putrefaciens. A nonspecific efflux of intracellular components such as adenosine triphosphate and beta-galactosidase was detected after the addition of protamine in gram-negative and gram-positive bacteria. Furthermore, protamine's antibacterial activity involves the interaction of polycationic peptides with anionic cell wall components and phospholipids in the cytoplasmic membrane.

Antibiotics, Gram-negative bacteria, Microbial metabolism

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Production of acylated homoserine lactones by psychrotrophic members of the Enterobacteriaceae isolated from foods

Article Abstract:

Many Enterobacteriaceae produce acylated homoserine lactones, which are used to coordinate colonization. In a study of 154 psychrotrophic Enterobacteriaceae isolated from foods, 116 produced these signal molecules.

Research, Enterobacteriaceae, Signal peptides

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