Regulation of the Xenopus labial homeodomain genes, HoxA1 and HoxD1: activation by retinoids and peptide growth factors

Article Abstract:

HoxA1, a Xenopus labial homeodomain gene, is present around the circumference of neurula stage embryos and in mid brain, hind brain endolymphatic duct and spinal cord. Another Xenopus labial homeodomain gene HoxD1 is expressed in dorsolateral and ventral ectoderm. Expression of both genes in the ectoderm and mesoderm of gastrula stages is significantly induced by retinoic acid, and this induction is independent of protein synthesis. Expression of HoxD1 in animal caps is induced by the peptide growth factors and they exert no influence on the expression of HoxA1.

Analysis, Physiological aspects, Growth factors, Genetic regulation, Retinoids

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Identification of a BMP inhibitor-responsive promoter module required for expression of the early neural gene zic1

Article Abstract:

A study conducted to identify the bone morphogenetic protein inhibitor-responsive promoter needed for expression of zic1 gene which codes for neural development in Xenopus is presented.

Promoters (Genetics), Bone morphogenetic proteins

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Tcf- and Vent-binding sites regulate geminin expression in the gastrula embryo

Article Abstract:

The role of Tcf- and Vent-binding sites in controlling the expression of geminin gene during neural development in Xenopus laevis early embryos is studied.

Embryology, Experimental, Embryological research, Binding sites (Biochemistry), Active sites (Biochemistry), Gastrulation

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