Retrovirus receptors

Article Abstract:

Retroviruses utilize a variety of apparently unrelated cell surface receptors to initiate infection. The receptor at the cell surface that acts as a inlet for virus entry into animal cells have become a focus of renewed interest due to the identification of receptor molecules. These receptors were first characterized not as molecules, but as genetic determinants of pseudotype or vector entry. The relationship between receptors is deduced from analyzing the serotype of viral envelope antigens with host range and with blocking of receptors by related viruses known as retroviral interference.

Cell receptors, Retroviruses

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Structure of the complete extracellular domain of the common beta subunit of the human GM-CSF, IL-3, and IL-5 receptors reveals a novel dimer configuration

Article Abstract:

Research has been conducted on the receptor systems for the hemopoietic cytokines GM-CSF, IL-3, and IL-5 consisting of the ligand-specific alpha receptor subunits which activate the shared beta(c) subunit. The structure of the complete beta(c) extracellular domain has been investigated and the results are reported.

Australia, Statistical Data Included, Physiological aspects, Cytokines, Ligands, Ligands (Chemistry)

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The organizer and beyond

Article Abstract:

The author reviews the publications on the embryonic dorsal blastopore lip (the organizer) signaling. The topics of interest include molecular analysis of the organizer, formation of the signaling boundaries and limb patterning.

Israel, Genetic aspects, Cells (Biology), Embryology, Experimental, Embryological research, Cells

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