mRNA for cardiac calcium channel is expressed during development of skeletal muscle

Article Abstract:

The expression of mRNA encoding the cardiac dihydropyridine-sensitive calcium channel in skeletal muscle developing in vivo and primary cultures derived from skeletal muscle was investigated. Expression of the mRNA at high concentration was detected in the earliest stage in vivo but diminished rapidly as myofibers mature. Also, there was concomitant diminishing of cardiac calcium channel mRNA. In contrast, mRNA for the skeletal muscle-specific calcium channel accumulates gradually in developing skeletal muscle.

Heart muscle, Myocardium

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Up-regulation of L-type Ca2+ channel associated with the development of elevated K+-mediated survival of superior cervical ganglion cells in vitro

Article Abstract:

Incubation of the mRNA of L-type calcium ion channels with nerve growth factor causes an increase in mRNA expression, which is correlated to in vitro existence of superior cervical ganglion (SCG) cells caused by K+, as revealed by semiquantitative PCR measurements. Both the pre- and postganglionic synapses in SCG, cells are strengthened due to this correlation.

Analysis, Ganglia

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