Signalling in the yeasts: an informational cascade with links to the filamentous fungi

Article Abstract:

A study was conducted on the different signalling pathways in both budding and fission yeasts to determine the role of mitogen-activated protein kinase (MAPK) cascade in the transduction various signals from the cell surface to the cell interior. Results showed that the response to a particular signal is highly specific with only few cross talks between pathways despite the multiplicity and high conservation of the MAPK cascades within a single cell. This indicates that MAPK cascades play an important role in regulating the pathogenicity of filamentous fungi.

Yeast fungi, Yeasts (Fungi)

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Cdc42: an essential rho-type GTPase controlling eukaryotic cell polarity

Article Abstract:

Cdc42p GTPase and Rho-type GTPases have been found to play an integral role in the signal transduction of cell polarity of major eukaryotic cells. Results gathered from an analysis involving cultured mammalian Cdc42p cells suggest that these strains create a positive stimulatory effect on cellular processes. Although the actual mechanism of cell polarity in eukaryotic cells is not yet known, it may be safe to conclude that these enzymes facilitate exogenous and endogenous signals to downstream effectors.

Analysis, Physiological aspects, Eukaryotic cells, Cells (Biology), Eukaryotes, G proteins, Polarity (Biology)

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Yeast carbon catabolite repression

Article Abstract:

Research was conducted to examine the mechanisms of carbon catabolite repression in Saccharomyces cerevisiae and other yeasts. Results showed that several elements are involved in the mechanism underlying catabolite repression and most of them are associated to the protein kinase Snf1, indicating that it is a central element in the different regulatory mechanisms. The Snf1 activity greatly decreases in the presence of glucose. The decrease is found to be related to the dephosphorylation of Snf1.

Yeast, Yeast (Food product), Protein kinases

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