Stimulation of strontium accumulation in linoleate-enriched Saccharomyces cerevisiae is a result of reduced Sr2+ efflux

Article Abstract:

The role of modified plasma membrane fatty acid composition in cellular strontium accumulation in Saccharomyces cerevisiae has been studied through the fatty acid enrichment method. Results indicate that the growth of S. cerevisiae in the presence of 1 mM linoleate produced cells that accumulated Sr2+ intracellularly at twice the rate of S. cerevisiae grown without a fatty acid supplement. This finding can be observed through a wide range of external Sr2+ concentrations.

Strontium

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Copper toxicity towards Saccharomyces cerevisiae: dependence on plasma membrane fatty acid composition

Article Abstract:

The sensitivity of Saccharomyces cerevisiae to copper (Cu) toxicity depends on the fatty acids present in its plasma membrane. The cells enriched with the diunsaturated fatty acid linoleate are highly prone to Cu-induced plasma membrane permeabilization. The release of cellular potassium ions by the linoleate-enriched cells is much higher than that from unenriched cells. The cells enriched with triunsaturated fatty acid linoleate are most sensitive to Cu toxicity.

Research, Observations

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Induction of lipid peroxidation during heavy metal stress in Saccharomyces cerevisiae and influence of plasma membrane fatty acid unsaturation

Article Abstract:

Increased membrane lipid peroxidation causes copper toxicity in Saccharomyces cerevisiae. The ability of the cells to cope with copper is compromised by induction of antioxidant defenses during respiratory adaptation and by membrane fatty acids. These findings are of great significance in the study of the environment because the fatty acid levels of microorganisms show great variation.

Analysis, Lipid peroxidation

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