Structure of the enabled/VASP homology 1 domain-peptide complex: a key component in the spatial control of the actin assembly

Article Abstract:

A study was conducted to determine the structure and physiological function of mammalians' Enabled/vasolidator-stimulated phosphoprotein (VASP) homology 1 (EVH1) domain-peptide complex. Results indicate that the EVH1 domain fold's structure is similar to that of pleckstrin homology domain, which is a membrane localization module. It was also found that EVH1 domains play an active role in the spatial control of actin assembly.

Mammals, Phosphoproteins

---

Ciboulot regulates actin assembly during Drosophila brain metamorphosis

Article Abstract:

Ciboulot (Cib), a novel actin binding protein, has been found to regulate actin assembly in Drosophila brain metamorphosis. A dynamic actin cytoskeleton is vital for changing cell shape in development. The Cib-actin complex is active in actin filament assembly only at the barbed end. Cib increases actin-based motility in vitro.

France, Statistical Data Included, Research, Genetic aspects, Brain, Drosophila, Cytoskeleton, Metamorphosis, Metamorphosis (Biology)

---

Remodeling of synaptic actin induced by photoconductive stimulation

Article Abstract:

Formation of new active presynaptic terminals of synaptic transmission machinery is demonstrated by video imaging of GFP-actin at individual synapses. Photoconductive stimulation model reveals that a single tetanus moves presynaptic actin toward synaptic junction while postsynaptic actin moving away from it.

United States, Models, Neural transmission, Synaptic transmission, Neuroplasticity, Synapses

Similar abstracts:

• Abstracts: Structure of the guanine nucleotide exchange factor Sec7 domain of human arno and analysis of the interaction with ARF GTPase
• Abstracts: Masking, unmasking, and regulated polyadenylation cooperate in the translational control of a dormant mRNA in mouse oocytes
• Abstracts: Deletion analysis of the selfish B chromosome, paternal sex ratio (PSR), in the parasitic wasp Nasonia vitripennis
• Abstracts: Sir-Ku-itous routes to make ends meet. Solution structure of the CIDE-N domain of CIDE-B and a model of CIDE-N/CIDE-N interactions in the DNA fragmentation pathway of apoptosis

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.