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Synergistic cooperation of TFE3 and Smad proteins in TGF-beta-induced transcription of the plasminogen activator inhibitor-1 gene

Article Abstract:

Synergistic cooperation of Smad and TFE3 proteins is a factor in TGF-beta-induced transcription of the inhibitor-1 gene, which is a plasminogen activator. A novel retrovirus-mediated expression cloning strategy has been developed and used to establish that TFE3, or transcription factor muE3, has a role in the activation of the PAI-1 promoter by TGF-beta.

Author: Lodish, Harvey F., Ansari, Dominic O., Hua, Xianxin, Liu, Xuedong
Publisher: Cold Spring Harbor Laboratory Press
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 1998
Observations, Proteins, Cellular signal transduction, Genetic regulation, Genetic transcription, Transcription (Genetics), Cell receptors, Plasminogen activators, Fibrinolytic agents

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Silencing of the xenogeneic DNA by H-NS-facilitation of lateral gene transfer in bacteria by a defense system that recognizes foreign DNA

Article Abstract:

The role of the lateral gene in bacterial evolution, the impact of environmental conditions and the possibility of the role of microorganisms are discussed.

Author: Fang, Ferric C., McClelland, Michael, Navarre, William Wiley, Libby, Stephen J.
Publisher: Cold Spring Harbor Laboratory Press
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2007
Biological Product (except Diagnostic) Manufacturing, Drugs, Deoxyribonucleic Acid, Genetic aspects, DNA, Microorganisms, Genetic transformation

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Subjects list: Analysis
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