"Tell me where is calcium bred": clarifying the roles of nuclear calcium

Article Abstract:

Ca2+ signal are generated by transport through the nuceloplasmic space and work as the pool for nuclear Ca2+, regulates specific Ca2+-dependent nuclear processes. Several factors contribute to the discrepancies associated with the cell-specific nature of nuclear-cytoplasmic Ca2+ exchanges, which include the stage of cell development, nuclear and cytosolic fluorescence. Moreover, results of several studies have presented evidence that gene expressions can also be determined by nuclear Ca2+.

Physiological aspects, Genetic aspects, Cells (Biology), Calcium ions, Cells, Cell nuclei, Cell nucleus, Ion exchange

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PIP2 and PIP3: complex roles at the cell surface

Article Abstract:

Phosphatidylinositol (4,5)-bisphosphate (PIP2) and phosphatidylinositol (3,4,5)-trisphosphate (PIP3) are membrane phospholipids that perform a variety of functions. PIP2 is a signaling molecule that is stimulated by hormones. PIP3 affects the downstream targets of the phosphoinositide 3 kinase pathway.

Research, Phospholipids, Membranes (Biology)

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Essential roles of S-nitrosothiols in vascular homeostasis and endotoxic shock

Article Abstract:

The S-nitrosothiols (SNO's) regulate innate immune and vascular homeostasis function and are cleared actively to ameliorate nitrosative stress. SNO plays an important role in endotoxic shock as well.

Diagnosis, Protein synthesis, Protein biosynthesis, Nitroso compounds, Vascular hemostatic disorders

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