Temperature-sensitive mutations demonstrate roles for yeast fibrillarin in pre-rRNA processing, pre-rRNA methylation, and ribosome assembly

Article Abstract:

Temperature-sensitive lethal point mutations were generated in the NOP1 yeast gene, which codes for a small nucleolar (sno) RNA-associated protein homologous to fibrillarin. Analysis of the mutations' effects on ribosome synthesis showed that NOP1 is involved in the cleavage of pre-rRNAs, methylation and pseudouuridylation of the rRNAs and assembly of the rRNAs with ribosomal proteins. It is proposed that NOP1 is required for pre-rRNA to adopt the correct conformation in order to undergo these various steps in ribosome synthesis.

Research, Ribosomal RNA, Yeast, Yeast (Food product), Ribosomes

---

RNA processing marches on

Article Abstract:

This review is a summary of the meetings on "Regulation of Messenger RNA Processing" held in Madrid from 2-4 October 2000. The role of RNA processing at the posttranscriptional level comprises of multifarious aspects of developmental stages including sex determination, apoptosis, maturation of immune response, and tissue-specific gene expression.

Scotland, Developmental biology, Metabolic regulation, RNA, Growth, Growth (Physiology), Growth regulators

---

Giving Meaning to movement

Article Abstract:

This review examines the evidence that support movement of plant transcription factors between plant cells. The mechanism is discussed with reference to SHORTROOT protein, which illustrates the signaling pathway for positional information transfer between root cell layers.

Biological transport, Plant cellular control mechanisms, Plant cell regulation

Similar abstracts:

• Abstracts: Diverse mutations in the gene for cartilage oligomeric matrix protein in the pseudoachondroplasia - multiple epiphyseal dysplasia disease spectrum
• Abstracts: The mating strategies of eastern screech-owls: a genetic analysis. A tale of two strategies: Life-history aspects of family strife
• Abstracts: Multivariate analysis of male mating success on morphometric traits and chromosome dosage in the grasshopper Sinipta dalmani
• Abstracts: Effects of pH on distribution of Listeria ribotypes in corn, hay, and Grass silage. Mycophenolic acid in silage
• Abstracts: Recombination between rRNA operons created most of the ribotype variation observed in the seventh pandemic clone of Vibrio cholerae

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.