The ATRs, ATMs, and TORs are giant HEAT repeat proteins

Article Abstract:

The authors discuss protein sequence analysis. Results demonstrate that this analysis describes non-kinase portions of ATM and Rad3 related, ataxia telangiectasia mutated and target of rapamycin as giant helical repeat domains which d iffer from one another by subtraction, rearrangement and addition of specific huntingtin, elongation factor 3, A subunit of protein phosphatase 2A and TOR1 repeat units.

Research and Development in the Physical, Engineering, and Life Sciences, Science & research, Molecular Biology, Research, Genetic aspects, Phosphatases, Amino acids

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Deciphering NAD-dependent deacetylases

Article Abstract:

The authors review the publications on the NAD-dependent deacetylases. The topics of interest include a high-resolution structure of the Archaeoglobus fulgidus Sir2-Af1 NAD-dependent protein deacetylase complexed with its cofactor NAD and the mechanism of the NAD-dependent deacetylation.

Statistical Data Included, Enzymes

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