The Caenorhabditis elegans unc-31 gene affects multiple nervous system-controlled functions

Article Abstract:

A study was done on a nematode worm, Caenorhabditis elegans, to determine the effect of unc-31 mutations on pharyngeal feeding motions. Pumping-constitutive mutants (Puc) were isolated in four independent mutagenesis experiments. Results showed four defects in the nervous system-controlled functions. Worms were lethargic, pumping-constitutive, defective in egg laying and in recovery from the dauer state. Tests showed that unc-31 mutants had correct body structure. However, it was possible that unc-31 mutations resulted in anatomical defects.

Research, Mutation (Biology), Mutation, Nematoda, Nematodes

---

The genetics of feeding in Caenorhabditis elegans

Article Abstract:

A genetic study of development and function of the excitable cells in the pharynx of Caenorhabditis elegans was reported. Worms with visible defects in pharyngeal feeding behavior were screened. Then, genetic mapping and complementation tests were used to identify 35 genes from 52 mutations. These were classified into three groups as pha, phm and eat genes based on the pharyngeal motion defects which were attributed to abnormal electrical excitability of the pharyngeal muscle membrane.

Animal anatomy, Worms, Worms (Animals)

---

Interacting genes required for pharyngeal excitation by motor neuron MC in Caenorhabditis elegans

Article Abstract:

The role of the MC neuron type in the control of pharyngeal pumping rhythm in Caenorhabditis elegans was determined. Two genes, eat-2 and eat-18, which eliminate MC function, were examined by pumping assays and statistical methods. Electropharyngeograms showed that MC transmits periodic excitatory postsynaptic potentials onto the pharynx by sending the neurotransmitter acetylcholine, which in turn, opens a nicotinic ACh receptor to excite the pharyngeal muscle.

Physiological aspects, Motor neurons, Excitation (Physiology)

Similar abstracts:

• Abstracts: Molecular and genetic analysis of unc-7, a Caenorhabditis elegans gene required for coordinated locomotion. Analysis of the Caenorhabditis elegans axonal guidance and outgrowth gene unc-33
• Abstracts: The isolation of mutagen-sensitive nuv mutants of Aspergillus nidulans and their effects on mitotic recombination

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.