Mitotic histone H3 phosphorylation by the NIMA kinase in Aspergillus nidulans

Article Abstract:

Results demonstrate that in Aspergillus nidulans NIMA kinase localized to chromatin, phosphorylates histone H3. Data further show that NIMA kinase phosphorylates serine-10 of histone H3 in vitro.

Research, Aspergillus, Chromosome banding

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The JIL-1 tandem kinase mediates histone H3 phosphorylation and is required for maintenance of chromatin structure in Drosophila

Article Abstract:

Research has been conducted on the chromatin kinase JIL-1 functions. The analysis of these functions has been carried out via generation of the allelic series of the hypomorphic and null mutations and the results indicate that JIL-1 kinase activity is required for maintaining the structure of the open chromatin region facilitating gene transcriptions.

Statistical Data Included, Genetic aspects, Chromatin, Genetic transcription, Transcription (Genetics), Drosophila, Cell research, Cytological research

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Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells

Article Abstract:

Research demonstrates that Aurora-A, belonging to the Aurora family kinases, is essential for mitotic entry and its activation in late G2 phase of the cell cycle recruits cyclin B1-Cdk1 complex to centrosomes, where it commits cells to mitosis. Furthermore, the Aurora-A binding protein Ajuba induces autophosphorylation and activation of Aurora-A and in the absence of Ajuba mitotic entry is inhibited.

Mitosis

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