The evolution of tandemly repetitive DNA: recombination rules

Article Abstract:

A model describing the evolutionary persistence of single tandemly repetitive DNA (TR-DNA) is analyzed. The study assumes that variable numbers of tandem repeats (VNTRs) can be grouped with satellite DNAs to create a class of TR-DNA. The evolutionary process is likewise assumed to flow from an unbiased recombinational process. Results show that misalignment constraint generates VNTR loci evolution including minisatellites. The results support nonrandom VNTR and other TR-DNA distributions in the human genome.

DNA

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Active mutator elements suppress the knotted phenotype and increase recombination at the Kn1-0 tandem duplication

Article Abstract:

Knotted-1 (KN1) locus mutations are analyzed. These mutations have an impact on the growth patterns of leaves. Tissues which protrude along the lateral veins of the maize leaf and displacement of ligule tissue from the blade and sheath junction mark Kn1-0 mutations. Such mutations emerge from tandem duplication of 17kb, where repetitions cover the total KN1 transcription unit. Mutant phenotypes can be decreased by inserting mutator (Mu) transposable elements at the junction.

Genetic aspects, Phenotype, Phenotypes, Plant mutation

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