Thermally regulated translational control of frq mediates aspects of temperature responses in the neurospora circadian clock

Article Abstract:

The effect of temperature on the circadian oscillators was determined using Neurospora strains. Two different forms of FRQ were used to analyze the different physiological aspects of circadian responses and the effect of temperature changes. FRQ level and the rate of protein synthesis increases as the temperature increases. Changes in the temperature can reset the circadian clock as an indirect effect of changing the level of FRQ. Changes in oscillation amplitude is also depndent on temperature changes.

Enzymes, Circadian rhythms, Codon, Codons, Enzyme regulation

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Alternative initiation of translation and time-specific phosphorylation yield multiple forms of the essential clock protein FREQUENCY

Article Abstract:

The effect of translational regulation and time-of-day specific phosphorylation on synthesis of essential clock protein Frequency (FRQ) was established by using the circadian oscillator of Neurospora. Translational initiation sites on the gene frq resulted to two similar but two functionally different forms of FRQ protein. The effects of phosphorylation on the size discrepancy of the two forms of FRQ was determined by the use of immunoprecipitation and Western blot analysis.

Genetic transcription, Transcription (Genetics), Phosphorylation

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Lessons from the genome sequence of Neurospora crassa: Tracing the path from genomic blueprint to multicellular organism

Article Abstract:

An analysis of over 1,100 of the approximately 10,000 predicted proteins encoded by the genome sequence of the filamentous fungus Neurospora crassa is presented. The basic features of the genome, including the automated assembly, gene calls and global gene analyses are summarized.

Science & research, Genetic aspects, Genomes, Nucleotide sequencing

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