Tissue fusion and cell sorting in embryonic development and disease: Biomedical implications

Article Abstract:

The role of adhesion molecules and cell dynamics in tissue fusion and cell sorting is discussed, providing examples of their impact in embryonic development. The concept of malignant invasion, a process whereby the elimination of boundaries and compartments results in intermixing of cells, in effect, cell sorting in reverse is discussed.

Genetic aspects, Membrane fusion, Embryology

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The collagen family members as cell adhesion proteins

Article Abstract:

The application of the various collagen family members of extracellular matrix proteins as cell adhesives is explained. These members are also found to be very useful for the normal development of bone, cartilage or breast tissue.

Biological Product (except Diagnostic) Manufacturing, Drugs, Collagen, Bones, Bone development

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The cadherin-catenin complex as a focal point of cell adhesion and signalling: new insights from three-dimensional structures

Article Abstract:

The essential mechanisms underlying cadherin-mediated cell interaction and catenin-mediated cellular signaling are examined. The beta-catenin recognition of other cellular factors shows a remarkable structural diversity.

Cell interaction, Cell interactions, Cell adhesion

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