Unique expression pattern of the FGF receptor 3 gene during mouse organogenesis

Article Abstract:

The unique expression pattern of fibroblast growth factor receptor 3 (FGFR3) during organogenesis was investigated using in situ hybridization analysis. FGFR3 was expressed in the germinal epithelium of the neural tube. However, at one day postpartum and in the adult brain, FGFR3 was expressed diffusely and localized in cells with morphologic characteristics of glia. In addition, high level expression in differentiating hair cells of the cochlear duct was detected. But the highest level of expression was found in the cartilage rudiments of developing bone.

Gene expression, Cell receptors

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Fibroblast growth factor influences the development and cycling of murine hair follicles

Article Abstract:

Histological analysis of mice treated with basic fibroblast growth factor (bFGF) indicates that the latter delays the development of hair follicles during the neonatal period. On the other hand, subjects treated with bovine serum albumin alone did not experience significant changes in hair growth patterns. The effect of bFGF on hair follicle growth does not seem to be due to changes in vascular formation.

Genetic aspects, Growth, Hair, Hair follicles

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A fat body-derived protein is selectively sulfated during transit to ovarian follicles in the stick insect Carausius morosus

Article Abstract:

Experimental studies using a monoclonal antibody developed against ovarian follicles of the stick insect Carausius morosus reveal that a fat body-derived 157-kDa polypeptide is selectively sulfated upon transfer to the ovarian follicle. This sulfated 157-kDa polypeptide helps develop extracellular matrix of the inter follicular cell channels and functions as binding sites for other hemolymph proteins.

Physiological aspects, Proteins, Insects, Ovaries

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