Vacuole biogenesis in Saccharomyces cerevisiae: Protein transport pathways to the yeast vacuole

Article Abstract:

The vacuole of Saccharomyces cerevisiae plays an important central role in the physiology of the organism. The biogenesis of the vacuole in S. cerevisiae is discussed, in particular, the processes involved in forming and transmitting the organelle. Transport pathways in the delivery of proteins to the vacuole are also discussed. This includes sorting of proteins from the lat Golgi to the vacuole, endocytosis of proteins and cytoplasm-to-vacuole targeting.

Observations, Proteins, Saccharomyces, Developmental cytology, Cell organelles, Organelles, Vacuoles

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Human immunodeficiency virus type 1 Nef: Adapting to intracellular trafficking pathways

Article Abstract:

Nef is a small myristoylated protein that binds to a collection of cellular factors and acts as an adaptor to generate novel protein interactions to accomplish specific functions. It generates pleiotrophic effects in the secretory and endocytic pathways that reprogram intracellular protein trafficking and provides an efficient platform for viral assembly.

HIV, Transport proteins, Structure, Chemical properties

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Molecular pathways in virus-induced cytokine production

Article Abstract:

The host response to viral infections is reflected in the production of cytokines and chemokines mediated by the interaction of cellular receptors and viral glycoproteins. Data reveal that viral RNA and viral proteins interfere with signal transduction pathways in the host leading to viral replication and expression of proinflammatory proteins.

Denmark, Statistical Data Included, Virus diseases, Inflammation, Inflammation mediators, Cytokines, Immune response, Immune response regulation

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