From blunderbuss to magic bullet

Article Abstract:

Combinatorial chemistry treats organic molecules as the composition of modules. Modules are examined in all possible combinations with a view to producing 'magic bullet' molecules that act specifically upon a given 'target molecule'. Developments in the science are detailed.

Innovations

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High and hooked

Article Abstract:

Researchers seeking to explain addictions to food, tobacco, heroin and cocaine are concentrating on the molecular biology of the brain's mesolimbic system. Dopamine receptor proteins may be the key to the mystery.

Physiological aspects, Drug abuse, Drug withdrawal symptoms, Substance withdrawal syndrome

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Utterly predictable

Article Abstract:

Ways of calculating the shape of protein molecules are examined in detail, including new developments in this field.

Analysis, Protein research

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