Antimicrobial drug discovery through bacteriophage genomics

Article Abstract:

A unique protein is developed that arrest critical cellular processes to commit bacterial host metabolism to phage reproduction applied to antibiotic discovery. The results of this development showed the growth inhibitory effect of phage polypeptides by a chemical compound, coupled with the plethora of phages on earth, will yield new antibiotics to combat infectious diseases.

Care and treatment, Communicable diseases, Discovery and exploration, Antimicrobial additives

---

Phage display extends its reach

Article Abstract:

The phage display is limited to the subset of proteins, because the phage coat is assembled in the periplasm, which could be overcome by targeting proteins for export through the signal recognition particle (SRP)-dependent pathway. It is suggested that SRP-dependent signal sequences are useful for efficient periplasmic expression of proteins for a wide variety of purposes.

Signal peptides, Molecular genetics

---

Reinventing phage therapy: Are the parts greater than the sum?

Article Abstract:

Research groups are concentrating on phage as adjunct therapies in the control of bacterial pathogens that have emerged as resistant to some. Several research groups are developing whole phage as alternative treatments, the isolation and optimization of purified phage components as antibacterial opens up new areas in the fight against bacterial infections.

Bacterial infections, Bacteria, Pathogenic, Pathogenic bacteria

Similar abstracts:

• Abstracts: An analysis of bidding in the Japanese government bond actions. Evidence of predictable behavior of security returns
• Abstracts: National pride: Cherish the thought. Debt and doom? The economics and psychology of humour
• Abstracts: Asymmetric corporate exposures to foreign exchange rate changes. Economic exposure and integrated risk management
• Abstracts: The impact of social influence and role expectations on shopping center patronage intentions. Goal-setting paradoxes? Trade-offs between working hard and working smart: the United States versus China
• Abstracts: Functional proteomic screens reveal an essential extracellular role for hsp90alpha in cancer cells invasiveness

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.