Fingerprinting the circulating repertoire of antibodies from cancer patients

Article Abstract:

The phage-display random-peptide libraries are used to screen peptides binding to the repertoire of antibodies purified from whole serum that is derived from prostate cancer patients. This fingerprinting procedure is used to uncover and validate a specific prognostic serological marker as well as its corresponding native antigen and this method is useful in identifying molecular targets for therapy against cancer.

Prostate cancer, Peptides, Tumor antigens, Tumour antigens

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Tunable antibodies

Article Abstract:

Monoclonal antibodies (mAbs) are widely used for targeting cancer cells. A study highlights the progress in generating effective anti-cancer antibodies by manipulating antibody binding affinity and their ability to support antibody dependent cellular cytotoxicity (ADCC).

Cancer cells, Monoclonal antibodies

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The rollercoaster ride to anti-cancer antibodies

Article Abstract:

Anticancer antibody development and effectiveness are discussed.

Product development, Care and treatment, Viral antibodies, Antibodies

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