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How does gene expression clustering work?

Article Abstract:

Gene expression clustering allows an open-ended exploration of the data, without getting lost among the thousands of individual genes. The quality of clustering result can be evaluated based on internal criteria based on various statistical properties of the clusters or external criteria that is, based on additional information that was not used in the clustering process itself.

Author: D'haeseleer, Patrik
Publisher: Nature Publishing Co.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2005
United States, Gene expression, Genetic research

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What are DNA sequence motifs?

Article Abstract:

Sequence motifs are short, recurring patterns in DNA that are presumed to have a biological function. Most of them indicate sequence-specific binding sites form proteins such as nucleases and transcriptional factors, while others do important processes at the RNA level, including ribosome, binding, mRNA processing and transcriptional termination.

Author: D'haeseleer, Patrik
Publisher: Nature Publishing Co.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2006
California, Analysis, Genetic transcription, Transcription (Genetics), RNA processing

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How does DNA sequence motif discovery work?

Article Abstract:

The subdivision of motif discovery algorithms into three distinct approaches namely enumeration, deterministic optimization and probabilistic optimization is described. A brief description regarding each of the three subdivisions are provided.

Author: D'haeseleer, Patrik
Publisher: Nature Publishing Co.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2006
Biological Product (except Diagnostic) Manufacturing, Nucleic Acid Derivatives, Nucleotides, Structure, Chemical properties, DNA synthesis

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Subjects list: Research, Nucleotide sequence, Base sequence
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