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Identification of in vivo DNA targets of chromatin proteins using tethered Dam methyltransferase

Article Abstract:

For the identification of DNA loci that interact in vivo with specific nuclear proteins in eukaryotes the researchers developed an innovative technique, called DamID.

Author: van Steensel, Bas, Henikoff, Steven
Publisher: Nature Publishing Co.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2000
Biological Product (except Diagnostic) Manufacturing, Cancer & Cell R&D, Deoxyribonucleic Acid, Cancer research, DNA

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Aptamers on the scaffold

Article Abstract:

Researchers performed isolated yeast aptamers, short peptide sequences expressed on a protein scaffold, to identify peptides that inhibit intracellular yeast signals. The protein peptides can be used as targets for new drugs being developed.

Publisher: Nature Publishing Co.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 1999

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Proteomics: translating genomics into products?

Article Abstract:

Researchers are questioning the capacity of proteomics to accelerate the identificaton of genetic targets for use in diagnosing disease and therapy.

Author: Dove, Allan
Publisher: Nature Publishing Co.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 1999
Brief Article

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Subjects list: United States, Cellular proteins, Medical research
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