Paramagnetic proteoliposomes containing a pure, native, and oriented seven-transmembrane segment protein, CCR5

Article Abstract:

Researchers from Boston, Mass. demonstrated that seven-transmembrane segment, G protein-coupled receptors have the potential of becoming targets during drug therapy.

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In vitro selection of signaling aptamers

Article Abstract:

Researchers in Texas developed nucleic acid-binding species (aptamers) for possible use in medical diagnostic procedures.

In-Vitro Diagnostic Substance Manufacturing, Diagnostic substances, Diagnostic Reagents

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Tyrosine sulfate trapped by amber

Article Abstract:

Scientists have described a system that allows selective incorporation of one simplest post-translation modification, sulfotyrosine, into proteins expressed in Escherichia coli. Sulfotyrosine mediates a number of critical protein-protein interactions, some of which are important targets for therapeutic intervention, which suggest that this system is useful in pharmaceutical applications.

Research, Bacterial proteins, Tyrosine metabolism, Protein-protein interactions

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