Stable antibody expression at therapeutic level using the 2A peptide

Article Abstract:

Therapeutic monoclonal antibodies (mAbs) are developed for the treatment of cancer and other diseases. A mAb delivery system that allows continuous production of a full-length antibody at high-concentrations in vivo after gene transfer is described.

Science & research, Research, Cancer, Monoclonal antibodies

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Synthesis of a poly (vinylpyrrolidone-co-dimethyl maleic anhydride) co-polymer and its application for renal drug targeting

Article Abstract:

A polymeric drug carrier, polyvinylpyrrolidone-co-dimethyl maleic anhydride is synthesized for use in renal drug delivery. The findings indicate that poly is a useful candidate as a targeting carrier for renal drug delivery systems.

United States, Pharmaceutical Preparation Manufacturing, Management dynamics, Pharmaceutical preparations, Drug Delivery Systems, Management, Company business management, Povidone

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Site-specific PEGylation of a lysine-deficient TNF-alpha with full bioactivity

Article Abstract:

A lysine-deficient tumor necrosis factor-alpha was developed and has stronger antitumor therapeutic abilities than wild-type tumor necrosis factor-alpha.

Japan, Tumor necrosis factor, Polyethylene glycol, Tumour necrosis factor

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