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Toward the generation of rod and cone photoreceptors from mouse, monkey and human embryonic stem cells

Article Abstract:

The in vitro effective generation of putative rod and cone photoreceptors from mouse, monkey and human embryonic stem (ES) cells by stepwise treatment of under defined culture conditions, in the absence of retinal tissues is presented. The observations of the analysis which are likely to aid the development of human ES cell-based transplantation therapies for retinal diseases are discussed.

Author: Sasai, Yoshiki, Yoshimura, Nagahisa, Watanabe, Kiichi, Wataya, Takafumi, Osakada, Fumitaka, Ikeda, Hanako, Mandai, Michiko, Akaike, Akiori, Takahasi, Masayo
Publisher: Nature Publishing Co.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2008
Retinal diseases, Photoreceptors

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Reprogramming by the numbers

Article Abstract:

The studies have shown that induced pluripotent stem (iPS) cells are indistinguishable from embryonic stem (ES) cells. The significance of iPS cells is described from three different points of view.

Author: Nishikawa, Shin-ichi
Publisher: Nature Publishing Co.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2007
Comparative analysis, Observations, Hematopoietic stem cells

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A ROCK inhibitor permits survival of dissociated human embryonic stem cells

Article Abstract:

The Rho-associated kinase (ROCK) inhibitor is applied to human embryonic stem (hES). The results show the survival of the cells even after cell dissociation.

Author: Nishikawa, Shin-ichi, Sasai, Yoshiki, Muguruma, Keiko, Watanabe, Kiichi, Ueno, Morio, Kamiya, Daisuke, Nishiyama, Ayaka, Matsumura, Michiru, Wataya, Takafumi, Takahashi, Jun B., Nishikawa, Satomi
Publisher: Nature Publishing Co.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2007
Cell culture

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Subjects list: Research, United States, Embryonic stem cells, Stem cell research
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