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Chemicals, plastics and rubber industries

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Comparison of the van der Waals and undulation interactions between uncharged lipid bilayers

Article Abstract:

A numerical analysis of the long-range interaction energies between neutral multilamellar lecithin systems has been conducted. The analysis was made in order to verify if the long-range swelling behavior that occurs between the two undulating lipid bilayer are really due to undulation repulsion. The results, which include a long-range van der Waals interaction that continues to be more than 1 order of magnitude greater than the measured undulation repulsion, suggest a different cause for the swelling.

Author: Ruckenstein, Eli, Walz, John Y.
Publisher: American Chemical Society
Publication Name: Journal of Physical Chemistry B
Subject: Chemicals, plastics and rubber industries
ISSN: 1520-6106
Year: 1999
Numerical analysis, Lipid membranes, Lecithin

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Surface equation of state for insoluble surfactant monolayers at the air/water interface

Article Abstract:

A theoretical model has been developed to analyze the liquid-expanded-liquid-condensed phase transition. The model treats the monolayer as a two-dimensional mixture composed of liquid-condensed domains, disordered molecules in the liquid-expanded state, and free sites. The new equation minimizes the Helmholtz free energy of the monolayer to obtain the equilibrium radius and the equilibrium area fraction of the domains as a function of the average molecular surface area.

Author: Ruckenstein, Eli, Li, Buqiang
Publisher: American Chemical Society
Publication Name: Journal of Physical Chemistry B
Subject: Chemicals, plastics and rubber industries
ISSN: 1520-6106
Year: 1998
Surface active agents, Surface chemistry

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Tunable delocalization of unpaired electrons of nitroxide radicals for sickle-cell drug improvements

Article Abstract:

Hydroxyurea, a drug approved to treat sickle cell diseases, benefits the patients by increasing the level of fetal hemoglobin via nitroxide radical pathway. An unpaired-electron--delocalization approach is reported to tune the stability of nitroxide radicals.

Author: Ruckenstein, Eli, Yun Hang Hu
Publisher: American Chemical Society
Publication Name: Journal of Physical Chemistry B
Subject: Chemicals, plastics and rubber industries
ISSN: 1520-6106
Year: 2007
Sickle cell anemia, Drug therapy, Hydroxyurea

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