Controlled hydrogel formation in the internal compartment of giant unilamellar vesicles

Article Abstract:

Hydrogel is generated within the internal compartment of giant unilamellar phospholipid vesicles (GUVs) by introducing poly (ethylene dioxythiophene) (PEDOT)/poly (styrene sulfonate) (PSS) polyelectrolyte into the vesicles and cross-linking with Ca(super 2+) ions. Vesicle fusion, electroporation and direct microinjection are the methods used for introducing calcium ions as cross-linking agent for the inducement of hydrogel formation.

All Other Basic Inorganic Chemical Manufacturing, Calcium & Compounds, Electric properties, Calcium compounds, Styrene

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Compaction process of calf thymus DNA by mixed cationic-zwitterionic liposomes: a physicochemical study

Article Abstract:

The compaction process of calf thymus DNA by cationic liposomes formed by a 1:1 mixture of cationic lipid and zwitterionic lipid is studied using conductometry, cryo-TEM and fluorescence spectroscopy. The results show that when the charge ratio between the cationic liposome and DNA reaches 1, the liposome membranes fuse and cause the lead DNA to collapse onto condensed structures together with the liposomes.

Drugs, Deoxyribonucleic Acid, Usage, DNA, Fluorescence spectroscopy, Structure

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Dynamic processes in endocytic transformation of a raft-exhibiting giant liposome

Article Abstract:

A real-time study observations of endocytic transformation in raft model membranes after the application of external stimuli is presented. Findings help to better understand the essential processes in domain-mediated internalization considering cellular endocytosis and membrane trafficking.

Osmotic pressure, Endocytosis

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