Direct measurement of chain order in single phospholipid mono- and bilayers with multiplex CARS

Article Abstract:

The study presents direct measurements of the thermodynamic state of single phospholipid mono- and bilayers based on the intrinsic vibrational properties of the molecules. The increased, shot-noise limited sensitivity of multiplex coherent anti-Strokes Raman scattering permits the acquisition of vibrational spectra of single lipid bilayers with a signal-to-noise ratio of 4 in 20 ms. The lipid chain order for both liquid-crystalline and get gel phase supported lipid bilayers is determined.

Usage, Raman effect

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Nanosecond field alignment of head group and water dipoles in electroporating phospholipids bilayers

Article Abstract:

Pore forming lipids and water in molecular dynamics simulations of a palmitoyloleoylphosphatidylcholine bilayer in a minimum porating electric field is tracked to investigate the mechanism of biological cell membrane electroporation at the nanosecond and nanometer scale. The study did not find any evidence in these simulations for a significant contribution to pore initiation.

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Effect of the barometric phase transition of a DMPA bilayer on the lipid/water interface: an atomistic description by molecular dynamics simulation

Article Abstract:

An atomistic depiction of a membrane of dimyristoylphosphatidic acid under different surface pressures obtained by molecular dynamics simulations is presented. The results suggest that the system structure is regulated by low surface pressure between opposite lipids interactions.

Composition, Molecular dynamics

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