Fluorescence study of DNA binding and bending by EcoRI DNA methyltransferase

Article Abstract:

The fluorescence anisotropy and fluorescence resonance energy transfer (FRET) techniques were applied to study the interaction between EcoRI DNA methyltransferase (M.EcoRI) and its target DNA in solution. The results showed that M.EcoRI had a higher binding affinity to the short dsDNA strand than to the long one, and its binding to DNA was primarily entropy-driven.

Methyltransferases, Structure

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Selective interactions of a few acridinium derivatives with single strand DNA: Study of photophysical and DNA binding interactions

Article Abstract:

The study results of acridinium derivatives indicate that they exhibit high solubility in buffer medium and efficiently distinguish between ssDNA and dsDNA through changes in fluorescence intensity and could have applications in fluorescent probes to understand various DNA-ligand interactions.

Acridine

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Effects of zinc binding on the conformational distribution of the amyloid-[beta] peptide based on molecular dynamics simulations

Article Abstract:

The comparative analysis of the apo-peptide and the holo-peptide which provide evidence for influence of zinc binding on the conformational distribution of amyloid-[beta] monomer dramatically is presented.

Primary nonferrous metals, not elsewhere classified, Secondary nonferrous metals, Peptides, Protein binding, Molecular dynamics, Amyloid beta-protein, Zinc, Zinc (Metal)

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