Role of hydrogen bonds in protein-DNA reorganization: Effect of nonplanar amino groups

Article Abstract:

A study on amino acid side chains and DNA bases containing amino groups as well as on specific hydrogen bonded residue pairs selected from high-resolution protein-DNA complex crystal structures is presented. It is indicated that the consideration of nonplanar amino groups leads to a more realistic scenario of hydrogen bonds occurring between protein and DNA residues.

Hydrogen bonding, Hydrogen bonds, Amino acids

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The N6-methyl group of adenine further increases the BI stability of DNA compared to C5-methyl groups

Article Abstract:

The study demonstrated the influence of the base modification on the conformational behavior of the DNA backbone. Molecular dynamics simulation of four different B-DNA dodecamers (d(DC)6, d(AT)6, d(G(5mCG)5C), and d(A(A(T6mA)5T) were performed to examine the influence of methyl groups on the B-DNA backbone behavior.

Adenine, Molecular dynamics

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Fluorescence relaxation dynamics of acridine orange in nanosized micellar systems and DNA

Article Abstract:

The fluorescence relaxation dynamics of acridine orange (AO) in reverse micelles (RM), micelles and DNA is studied using fluorescence spectroscopy. Two types of AOs are located in the nonpolar oil phase and at the interface.

Micelles, Relaxation phenomena, Relaxation (Physics), Structure, Acridine, Report

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