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Enantiomeric recognition of amine compounds by chiral macrocyclic receptors

Article Abstract:

Chiral macrocyclic compounds are used in the recognition and separation of amine compounds, important components of protein synthesis, enzyme systems, and other biomolecular interactions. Chiral macrocycles form stable complexes with enantiomers without significant interaction and repel other enantiomeric complexes. Low conformational flexibility promotes selective enantiomeric recognition.

Author: Izatt, Reed M., Bradshaw, Jerald S., Zhang, Xian Xin
Publisher: American Chemical Society
Publication Name: Chemical Reviews
Subject: Chemistry
ISSN: 0009-2665
Year: 1997
Enantiomers

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Chiral separations in capillary electrophoresis

Article Abstract:

This review addresses the developmental aspects and the current status of electrophoretic chiral separations with reference to capillary zone electrophoresis, capillary isotachophoresis, and modern electrophoretic methods. Separation methods for chiral compounds using cyclodextrins, as a chiral selector of choice in separation systems, are discussed.

Author: Vespalec, Radim, Bocek, Petr
Publisher: American Chemical Society
Publication Name: Chemical Reviews
Subject: Chemistry
ISSN: 0009-2665
Year: 2000
Czech Republic, Statistical Data Included, Methods, Cyclodextrins, Polysaccharides

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DNA diagnostics by capillary electrophoresis

Article Abstract:

The article discusses the technique of capillary electrophoresis (CE), which is commonly used in DNA and clinical diagnostics. The approach is found to be extremely efficient and can be easily done at low-operation costs

Author: Bocek, Petr, Kleparnik, Karel
Publisher: American Chemical Society
Publication Name: Chemical Reviews
Subject: Chemistry
ISSN: 0009-2665
Year: 2007
Science & research, Research, DNA testing, DNA identification

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Subjects list: Analysis, Chirality, Crown ethers, Usage, Electrophoresis
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