Enantioselective enzymatic desymmetrizations in organic synthesis

Article Abstract:

The developments made in the use of biocatalysts for the desymmetrization of meso and prochiral compounds from 1990 onwards are discussed. It is strongly believed that genetic engineering techniques will continue to play a major role in the future research of enzymatic biocatalysis but without detriment to other more traditional approaches such as medium engineering and the screening for new biocatalysts.

Research and Development in the Physical, Engineering, and Life Sciences, Science & research, Genetic Engineering, Research, Organic compounds, Organic compound synthesis, Enzymatic analysis

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Palladium-assisted routes to nucleosides

Article Abstract:

The authors review the publications on biological activity of nucleosides and their phosphorylated derivatives. The topics of interest include palladium-assisted modifications on nucleosides, and the use of nucleosides in palladium cross-coupling reactions.

France, Primary nonferrous metals, not elsewhere classified, Primary Smelting and Refining of Nonferrous Metal (except Copper and Aluminum), Biological Product (except Diagnostic) Manufacturing, Palladium, Nucleic Acid Derivatives, Precious metal products, Chemical reactions, Properties, Structure, Chemical properties, Chemical compounds

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Biocatalytic selective modifications of conventional nucleosides, carbocyclic nucleosides, and C-nucleosides

Article Abstract:

The authors review the publications on the nucleosides, the fundamental building blocks of biological systems. The topics of interest include the nucleoside analogue synthesis via enzymatic procedures.

Spain, Statistical Data Included, Physiological aspects, Enzymes, Carbon

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