Filamentous phage display in the new millennium

Article Abstract:

The use of the filamentous bacteriophage M13 and its close relative fd, peptides and proteins that are displayed on the surface of other bacteriophages and eukaryotic viruses are reviewed. Phage could be introduced into the animal's system through a number of means including injection, ventilation and gavage, and after a brief time period, tissue biopsies are collected, homogenized, and used to infect bacteria for phage amplification and subsequent rounds of selection.

Illinois, Analysis, Physiological aspects, Bacteriophages, Gene amplification, Filamentous bacteria

---

2-deoxystreptamine: Central scaffold of aminoglycoside antibiotics

Article Abstract:

A key feature of the aminoglycoside antibiotics is a 1,3-diaminocyclohexanetriol termed as streptamine or, in cases where the 1-hydroxy function is deoxygenated as in most aminoglycosides, 2-deoxystreptamine. In general, aminoglycosides show a strong synergistic effect upon coadministration with penicillin, a particularly useful combination for treatment of patients with infections of unknown origin.

Methods, Biosynthesis, Aminoglycosides

---

Syntheses around the transglycosylation step in peptidoglycan biosynthesis

Article Abstract:

The total syntheses of lipid II and analogues, which are acceptor substrates of the transglycolases and of compounds that interfere with the transglycosylation reaction, are described. The transglycolases involved in peptidoglycan biosynthesis are promising targets for new anti-infectives and their synthesis would help in understanding their structure and their role as antibiotic.

Peptidoglycans, Glycosylation, Lipids, Lipid synthesis, Structure, Chemical properties

Similar abstracts:

• Abstracts: New developments in the coordination chemistry of inorganic selenide and telluride ligands. Cycloheptatriene and -enyl complexes of the early transition metals
• Abstracts: Heterogenous photocatalysis. Many-body approaches for simulating coherent nonlinear spectroscopies of electronic and vibrational excitons
• Abstracts: New perspectives in the chemistry and biochemistry of the tunichromes and related compounds. Chemistry and biochemistry of type 2 diabetes
• Abstracts: Construction of enantiopure pyrrolidine ring system via asymmetric [3+2]-cycloaddition of azomethine ylides. Alkylidenecarbenes, alkylidenecarbenoids, dagger and competing species: which is responsible for vinylic nucleophilic substitution, [1 plus 2] cycloadditions, 1,5-CH insertion and the Fritsch-Buttenberg-wiechell rearrangement?
• Abstracts: Role of the surface in luminescent processes. Enzymatic biofuel cells for implantable and microscale devices

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.