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Engineering and manufacturing industries

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Abstracts » Engineering and manufacturing industries

Deciphering the mechanisms of therapeutic protein production

Article Abstract:

The rising demand for therapeutic recombinant proteins is driving further research in chinese hamster ovary (CHO) cell biology. More R&D efforts are projected in order to enhance production capacity. Researches in CHO cells, as well as the challenges and solutions concerning pharmaceutical companies and medical researchers are presented.

Author: Kayser, Kevin J., Caple, Matthew V., Allison, Daniel W., Borgschulte, Trissa, Bausch, Christoph L., Bahr, Scott M.
Publisher: American Institute of Chemical Engineers
Publication Name: Chemical Engineering Progress
Subject: Engineering and manufacturing industries
ISSN: 0360-7275
Year: 2007
Manufacturing processes, Cellular Biology, Production processes, Ovaries, Cytology

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Recombinant protein therapeutics from CHO cells - 20 years and counting

Article Abstract:

The synthesis of recombinant therapeutic proteins from chinese hamster ovary (CHO) cells started in 1987, and since then several biologics have been produced in this cell line. The progression of research in CHO cells is discussed, from its history to current practices to future challenges.

Author: Hu, Wei-Shou, Yap, Miranda G.S., Jayapal, Karthik P., Wlaschin, Katie F.
Publisher: American Institute of Chemical Engineers
Publication Name: Chemical Engineering Progress
Subject: Engineering and manufacturing industries
ISSN: 0360-7275
Year: 2007
History, Cell lines

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Direct-bacterial approach holds promise for rapid antibody development

Article Abstract:

The details of the disease-fighting antibodies mass production method developed by the University of Texas at Austin are presented.

Publisher: American Institute of Chemical Engineers
Publication Name: Chemical Engineering Progress
Subject: Engineering and manufacturing industries
ISSN: 0360-7275
Year: 2007
Texas, Analysis, Viral antibodies, Antibodies, University of Texas at Austin

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Subjects list: Research, United States, Forecasts and trends, Market trend/market analysis, Medical research, Recombinant proteins, Hamsters, Medicine, Experimental
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