Target Discovery using bioinformatics

Article Abstract:

This article discusses the postgenomic era in pharmaceutical research and the impact of bioinformatics in terms of new drug target identification and drug discovery. The process of identifying biochemical targets for drug design consists of data collation and data analysis and searching sequences encoding medically relevant "drug-susceptible targets.

United Kingdom, Usage, Pharmaceutical industry, Algorithms, Computer science, Computational biology

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Less bleach-- brighter paper

Article Abstract:

This article discusses a new process to bleach paper, which uses less hydrogen peroxide, carries low implementation costs, and does not require new equipment. The process is called modified peroxide or P(sub)M process, which increases the pulp brightness by 2 to 3 points on the ISO scale with savings in production costs.

Innovations, Manufacturing processes, Manufacturing, Paper industry, Papermaking, Paper finishing

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One man's war on cancer

Article Abstract:

This article focuses on the relationship between apoptosis and cancer and the implications of the "inhibitor of apoptosis-proteins" (IAP) in carcinogenesis. Crystal structure of the second mitochondria-derived activator of caspaces (Smac) and IAP complex is presented.

Cancer research, Physiological aspects, Cell death, Cancer, Proteins, Protein structure, Enzyme inhibitors

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