Interaction of the hemochromatosis gene product HFE with transferrin receptor modulates cellular iron metabolism

Article Abstract:

More is known about the genetic defects in iron overload disease or hereditary hemochromatosis (HH).The mutation within the region of chromosome 6 eventually led to the discovery of a new major histocompatibility class-I-like protein, called HFE. The majority of HH patients have the mutated HFE. Researchers have gained further insight into the details of iron absorption within the intestinal system, such as the loss of iron-binding proteins and the action of transferrin receptor in the cell membrane.

Research, Genetic aspects, Hemochromatosis, Chromosome abnormalities, Metabolism, Inborn errors of, Inborn errors of metabolism

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Fatigue of anemia

Article Abstract:

The physiological effects of iron deficiency anemia on the human body and mind are examined. The author maintains that iron influences human energy and people who suffer iron deficiency anemia are more prone to physical and mental fatigue, and women, growing children, and vegetarians are at high risk of developing anemia.

Health aspects, Women, Children, Women's health, Vegetarians, Child health, Iron deficiency anemia

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Discovery of the ceruloplasmin homologue hephaestin: new insight into the copper/iron connection

Article Abstract:

Research presented concerns the impact of copper in the human body on iron metabolism, focusing on the physiological aspects of the formation of hemoglobin. Topics addressed include the discovery of hephaestin and its role in iron absorption.

Hemoglobin, Hemoglobins, Copper in the body, Copper (Nutrient)

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