Function of the bone protein osteocalcin: definitive evidence

Article Abstract:

The bone protein osteocalcin may limit bone matrix formation without impacting resorption or excessive mineralization, according to animal models. Mice bred without the genes for osteocalcin showed increased bone strength and size. Since osteocalcin negatively regulates bone formation, therapeutic approaches include blocking osteocalcin action in conjunction with estrogen replacement therapy.

Bones, Bone density, Proteins, Physiological regulation, Protein synthesis, Biomineralization

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Transport of retinoids by the interphotoreceptor retinoid-binding protein

Article Abstract:

Retinoids are transported by the interphotoreceptor retinoid-binding protein between retinal pigment epithelium and the rod outer segment. A molecular mechanism of this process has been proposed utilizing the physical and chemical properties of retinol and pure interphotoreceptor retinoid-binding protein.

Research, Interphotoreceptor retinoid-binding protein

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