Lipoprotein metabolism influenced by training-induced changes in human skeletal muscle

Article Abstract:

This experiment on the skeletal muscle of normal human volunteers studied the effect training has on the muscles of one knee compared to the untrained muscles of the opposite leg. The study examines the level of several lipoproteins in the muscle. This method is used to compare levels of these molecules in trained and untrained leg muscles both at rest and during exercise. The authors conclude that the lipoprotein profiles associated with endurance training are, to a large extent, explainable by changes in the skeletal muscle tissue brought about by training.

Lipoproteins, Physical education and training, Physical education

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Differing erythrocyte membrane skeletal protein defects in alpha and beta thalassemia

Article Abstract:

In individuals who have inherited a single thalassemia (an anemia) associated chromosome the mild irregularity of the red blood cell may be related to damage to the red blood cell membrane. Thirteen patients with one form of Thalassemia were compared with 20 normal individuals. The findings indicate that specific, localized defects exist in the skeletal structures of Thalassemia red cells, implying that different mechanisms may be involved in the various Thalassemias.

Abnormalities, Causes of, Erythrocytes, Red blood cells, Thalassemia

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Redirection of prostaglandin endoperoxide metabolism at the platelet-vascular interface in man

Article Abstract:

A specific prostaglandin, prostacyclin (PG12) is an inhibitor of platelet function in the laboratory. This study explores this effect in 13 healthy individuals. Results indicate that at the site of a damaged blood vessel wall, there was an effect on platelet function related to a factor required in the formation of a prostaglandin.

Prostaglandins, Blood platelets, Prostacyclin

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