A 51-year-old man with the adult respiratory distress syndrome

Article Abstract:

A businessman with adult respiratory syndrome died of multiple organ failure caused by an atypical presentation of bacterial pneumonia. The 51-year-old man was hospitalized with a recent history of chills and breathing difficulties. His blood pressure dropped steadily while the heart beat accelerated. Urine output was minimal and chest X-rays revealed progressive lung disease. The patient died despite antibiotics and maximum drug therapy during the second episode of heart failure. Fibrous tissues in the heart and lungs, found at autopsy, indicated a fatal organ-conduction problem that worsened the course of the bacterial infection. The bacterium in question was group A beta-hemolytic streptococcus. Some bronchial scarring may have predisposed the patient to pneumonia, possibly related to having had sarcoidosis thirty years earlier.

Streptococcal infections, Complications and side effects, Acute respiratory distress syndrome, Adult respiratory distress syndrome, Bacterial pneumonia

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A 60-year-old man with pulmonary infiltrates after a bone marrow transplantation

Article Abstract:

A 60-year-old man was hospitalized because he had fluid in his lungs and was producing greenish-brown sputum. He had a history of multiple myeloma, for which he received chemotherapy and a bone marrow transplant. A sample of lung fluid collected by bronchoalveolar lavage tested positive for Hemophilus influenzae and he was given antibiotics. However, he did not respond to the drugs and his condition worsened so much that he had to be put on a ventilator. An open lung biopsy revealed that he had lung damage that was consistent with drug-induced lung disease. Busulfan was the most likely candidate. He did not respond to corticosteroids and eventually died.

Health aspects, Causes of, Lung diseases, Chemotherapy, Multiple myeloma, Busulfan

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