A More Accurate Method To Estimate Glomerular Filtration Rate from Serum Creatinine: A New Prediction Equation

Article Abstract:

A mathematical equation using serum creatinine concentration and demographic factors may more accurately estimate the glomerular filtration rate (GFR) of the kidneys than the creatinine clearance value alone. GFR is a measure of kidney function. Researchers developed the equation using data from 1,070 patients, then tested it in 558 patients. A combination of age, gender, ethnicity, serum urea nitrogen levels, serum albumin levels, and creatinine concentrations closely estimated the GFR, while the creatinine clearance value alone either overestimated or underestimated GFR, depending on the way it was calculated.

Models, Measurement, Creatinine, Kidney function tests

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Assessing kidney function - measured and estimated glomerular filtration rate

Article Abstract:

Organizations recommend the use of equations that estimate the glomerular filtration rate (GFR) to facilitate the detection, evaluation, and management of chronic kidney disease. A review on the strengths and weaknesses of existing methods of measuring and estimating GFR as applied to chronic kidney disease is presented.

Care and treatment, Diagnosis, Disease/Disorder overview

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Prevalence of chronic kidney disease in the United States

Article Abstract:

The effect of the increasing prevalence of diabetes and changes in hypertension and obesity as explanatory variables for changes in chronic kidney disease prevalence in the U.S. is discussed.

Science & research, Research, Hypertension, Risk factors, Diabetes, Diabetes mellitus, Obesity, Clinical report

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