A general practice trial of health education advice and HRT to prevent bone loss

Article Abstract:

Women aged between 48 and 52 with lower-than-average bone density were offered hormone replacement therapy (HRT) to see if the treatment improved their condition. Women also had to take extra calcium and do moderate exercise. HRT appears to reduce menopausal symptoms such as hot flushes, though the women tended to gain weight. After the two year study, the women taking HRT had increased bone density by 20% compared to the control group, which showed a 2% drop in density. Women should be encouraged to exercise as well as take HRT. A larger study is needed to confirm these results.

Care and treatment, Usage, Hormone therapy, Postmenopausal women

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Rapid Recovery of Bone Mass in Hypercalciuric, Osteoporotic Men Treated with Hydrochlorothiazide

Article Abstract:

Hydrochlorothiazide may effectively increase bone mineral density and correct hypercalciuria and osteoporosis in men. Hypercalciuria is the excessive loss of calcium in the urine, which can lead to brittle bone disease. Researchers treated five patients with the diuretic drug hydrochlorothiazide. Bone mineral density increased 3-8% per year during treatment, and the loss of calcium was arrested.

United States, Hydrochlorothiazide, Hypercalciuria

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Once-a-week alendronate (Fosamax)

Article Abstract:

The FDA has approved 35-milligram and 70-milligram tablets of Fosamax so the drug can be taken once a week instead of every day. This should lower the risk of adverse effects from the drug, which is used to treat osteoporosis.

Product/Service Evaluation, Fosamax (Medication)

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